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Mania as a Rare Adverse Event Secondary to Steroid Eye Drops
Moayyad Alsalem1,2,3, Majed A Alharbi4,5, Rayan A Alshareef6
1Psychiatry Section, Department of Medicine, King Abdulaziz Medical City, Ministry of the National Guard-Health Affairs, Jeddah, Saudi Arabia.
Case Reports in Psychiatry
|June 27, 2022
Summary
Glucocorticoids (GCs) can cause psychiatric side effects like mania. A rare case showed a 75-year-old woman recovered from GC-induced mania with olanzapine after cataract surgery.
Area of Science:
- Ophthalmology
- Psychiatry
- Pharmacology
Background:
- Glucocorticoids (GCs) are widely used for various conditions.
- Psychiatric adverse effects, including mania, are known complications of GC therapy.
- These effects often manifest early and may reverse upon GC discontinuation.
Observation:
- A rare case of a 75-year-old woman developed mania.
- The patient was undergoing treatment with glucocorticoid (GC) eye drops post-cataract surgery.
- Symptoms appeared during the course of GC treatment.
Findings:
- Discontinuation of prednisolone and administration of olanzapine led to rapid recovery.
- The patient's manic symptoms resolved within one week.
- Steroid-induced mania was diagnosed after olanzapine was stopped.
Implications:
- Highlights the potential for even topical GCs to cause significant psychiatric disturbances.
- Emphasizes the importance of monitoring for psychiatric side effects during GC therapy.
- Suggests olanzapine as a potential treatment for steroid-induced mania.
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