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Published on: October 25, 2024
Gastrointestinal tuberculosis presenting as acute abdomen: a case report
Sofia Ridolfo1, Francesco Cammarata2, Alessandro M Bonomi2
1Department of Gastroenterology, Luigi Sacco University Hospital, Milan, Italy.
Intestinal tuberculosis (ITB) can mimic Crohn's disease and present as a chronic or acute condition. Early diagnosis via targeted endoscopic biopsies is crucial for effective treatment and surgical emergency management.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Surgical Pathology
Background:
- Intestinal tuberculosis (ITB) poses a significant diagnostic challenge.
- It often mimics other gastrointestinal conditions like Crohn's disease (CD).
- ITB can manifest as a chronic illness or a life-threatening acute condition.
Observation:
- A 29-year-old woman presented with acute abdominal pain, fever, and weight loss.
- Initial CT scans and colonoscopies were inconclusive.
- The patient's condition deteriorated, leading to sepsis and emergency surgery.
Findings:
- Pathological and microbiological analyses confirmed gastrointestinal tuberculosis.
- While granulomas with caseation/necrosis aid diagnosis, preoperative identification remains difficult.
- Targeted endoscopic biopsies of ulcerous lesions proved essential for diagnosis.
Implications:
- Acute intestinal tuberculosis necessitates emergency surgical intervention.
- Diagnostic strategies must differentiate ITB from CD.
- Biopsy site selection during endoscopy is critical for accurate ITB diagnosis.
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