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A Scalable Balz-Schiemann Reaction Protocol in a Continuous Flow Reactor

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Published on: February 10, 2023

Safety Criteria for Solid-Liquid Heterogeneous Systems in Semibatch Reactors.

Zheng Ran¹, Lei Ni¹, Yong Pan¹

¹College of Safety Science and Engineering, Nanjing Tech University, Nanjing, Jiangsu 211816, China.

|June 27, 2022

Summary

This summary is machine-generated.

This study proposes new safety criteria to prevent thermal runaway in semibatch reactors for solid-liquid exothermic reactions. Enhanced models and experimental validation provide guidance for safer chemical process design.

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Area of Science:

Chemical Engineering
Reaction Engineering
Process Safety

Background:

Exothermic reactions in semibatch reactors pose risks of thermal runaway due to energy accumulation or secondary reactions.
Existing safety criteria may not adequately address the complexities of solid-liquid reactions.

Purpose of the Study:

To develop and validate novel safety criteria for solid-liquid exothermic reactions in semibatch reactors.
To enhance understanding of thermal behavior and prevent hazardous runaway reactions.

Main Methods:

Development of a new energy and mass balance model for solid-liquid reactions.
Simulation modeling to establish thermal runaway criteria.
Experimental validation using citric acid-sodium hydroxide neutralization.

Main Results:

Established improved criteria for safety boundary and temperature diagrams.
Demonstrated the significant influence of dissolution heat on reaction thermal behavior.
Validated the proposed criteria through experimental determination of critical parameters.

Conclusions:

The developed safety criteria offer practical guidance for chemical process optimization.
The findings contribute to enhanced safety design in semibatch reactor operations.
Accurate modeling of dissolution heat is crucial for predicting thermal runaway in these systems.