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Updated: Sep 6, 2025

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM
Published on: August 5, 2009
Speckle Noise Removal Model Based on Diffusion Equation and Convolutional Neural Network
Abstract:
The image denoising model based on convolutional neural network (CNN) can achieve a good denoising effect. However, its robustness is poor, and it is not suitable for direct noise removal tasks. Differently, the image denoising method based on the diffusion equation is more stable and has theoretical guarantees. In order to give full play to the advantages of CNN and diffusion equation in image denoising, this paper proposes a speckle noise denoising model via a combination of the two tools. Firstly, based on the mathematical model of speckle noise, a class of neural network speckle noise removal model which mixes residual learning and structure learning is proposed using image decomposition theory. Then, in order to solve the hyperparameter problem that the model depends on noise variance, a noise variance estimation algorithm based on a nonlinear diffusion equation is proposed. Finally, a speckle noise denoising model based on diffusion equation and CNN is obtained. Numerical simulation experiments verify the accuracy of the variance estimation algorithm and also the denoising effect and practical application value of the proposed method.
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