Related Experiment Video
Updated: Sep 6, 2025
10:10
A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
19.1K
Pseudotumoural pulmonary tuberculosis: a case series.
S Zayet1, A Berriche1, L Ammari1
1Infectious Diseases Department, La Ranta Hospital, 1007, Tunis, Tunisia.
IJID Regions
|June 27, 2022
Summary
Tumour-like pulmonary tuberculosis can mimic lung cancer in patients with or without human immunodeficiency virus (HIV) infection. Prompt diagnosis and antimycobacterial therapy led to successful treatment in all reported cases, including those with uncontrolled HIV.
Area of Science:
- Pulmonology
- Infectious Diseases
- Oncology
Background:
- Pulmonary tuberculosis can present with atypical radiological findings, mimicking lung carcinoma.
- Distinguishing between tuberculosis and lung cancer is crucial for appropriate patient management.
Observation:
- Three cases of tumour-like pulmonary tuberculosis are presented.
- Two patients had advanced human immunodeficiency virus (HIV) infection, one with uncontrolled HIV-1.
- One patient was immunocompetent.
Findings:
- Patients presented with general and respiratory symptoms, and imaging suggested lung cancer.
- Diagnosis was confirmed via microbiological and/or histological examination.
- One case involved disseminated tuberculosis.
Implications:
- This presentation highlights the importance of considering tuberculosis in the differential diagnosis of lung masses, even in immunocompetent individuals.
- Successful treatment with antimycobacterial therapy and HIV control was achieved in all cases.
- Early and accurate diagnosis is key for effective management of this challenging presentation.
Keywords:
EfavirenzHuman immunodeficiency virusLung carcinomaPseudotumouralPulmonary massTuberculosisMore Related Videos
Related Concept Videos
01:29Pulmonary Tuberculosis I
318
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
318
01:28Pulmonary Tuberculosis II
335
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
335
01:31Pulmonary Tuberculosis III
432
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
432
01:28Pulmonary Tuberculosis V
235
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
235
01:26Pulmonary Tuberculosis IV
195
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
195
01:17Other Pulmonary Disorders
905
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
905