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Practical Workflow for Cardiovascular Assessment and Follow-Up in Kawasaki Disease Based on Expert Opinion

Diana van Stijn1, R Nils Planken2, Maarten Groenink2,3

  • 1Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, Netherlands.

Frontiers in Pediatrics
|June 27, 2022
PubMed

Insights

Kawasaki disease (KD) can lead to coronary artery aneurysms (CAA) and cardiac complications. An integrated cardiovascular program is essential for early identification and tailored management of KD patients with coronary artery pathology.

Area of Science:

  • Cardiology
  • Pediatrics
  • Infectious Diseases

Background:

  • Untreated Kawasaki disease (KD) affects approximately 25% of patients, leading to coronary artery pathology, particularly coronary artery aneurysms (CAA).
  • Severe CAA in KD patients increases the risk of myocardial ischemia, infarction, and sudden cardiac death.
  • Accurate identification of coronary artery pathology is critical for reducing cardiac complications in KD patients.

Purpose of the Study:

  • To develop a practical, patient-specific workflow for the cardiovascular assessment of Kawasaki disease patients.
  • To integrate expert opinions from a multidisciplinary panel for comprehensive KD patient management.
  • To provide a tailored approach based on the severity of coronary artery pathology.

Main Methods:

  • Expert consensus from pediatric cardiologists, infectious disease specialists, and radiology experts.
  • Analysis of existing literature and current guidelines for KD management.
  • Development of a step-by-step, integrated cardiovascular follow-up approach.

Main Results:

  • A practical workflow for cardiovascular assessment in KD patients was established.
  • Expert opinions were synthesized into a multidisciplinary approach.
  • The workflow emphasizes patient-specific, step-by-step management.

Conclusions:

  • An integrated, multidisciplinary cardiovascular follow-up approach for KD patients has been developed.
  • This approach is based on expert opinion and tailored to individual patient needs.
  • The presented workflow aims to improve the management of coronary artery pathology in KD.
Abstract

Keywords:
Kawasaki diseasecardiovascular assessmentcoronary artery aneurysmsimagingmucocutaneous lymph node syndrome

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