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Related Experiment Video

Updated: Sep 6, 2025

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees
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Multifunctional Smart Bone Implants: Fiction or Future?-A New Perspective.

Inês Peres1, Pedro Rolo1, Marco P Soares Dos Santos1

  • 1Department of Mechanical Engineering, Centre for Mechanical Technology and Automation (TEMA), University of Aveiro, Aveiro, Portugal.

Frontiers in Bioengineering and Biotechnology
|June 27, 2022
PubMed
Summary
This summary is machine-generated.

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Bone Remodeling01:40

Bone Remodeling

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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A millimetre-scale capacitive biosensing and biophysical stimulation system for emerging bioelectronic bone implants.

Journal of the Royal Society, Interface·2024

Instrumented active implants represent the future of orthopedic bone devices. These smart, externally controlled implants offer multifunctional capabilities to reduce implant failure rates.

Area of Science:

  • Biomedical Engineering
  • Orthopaedic Surgery
  • Materials Science

Background:

  • Implantable medical devices are crucial for bioapplications, particularly in orthopaedics.
  • Current implant technologies include non-instrumented passive/active and instrumented passive/active implants.
  • High implant failure rates (exceeding 10%) necessitate advancements in implant design.

Purpose of the Study:

  • To propose instrumented active implants as the next technological revolution in bone replacement.
  • To present a new perspective on implant technology, emphasizing a hybrid architecture.
  • To highlight the importance of smart instrumentation, smart coatings, and extracorporeal control.

Main Methods:

  • This perspective paper reviews existing implant methodologies.
Keywords:
bioelectonic implantsbiointegrationimplant technologyinstrumented medical devicesmart implants

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  • It analyzes the potential of different implant designs to mitigate failure rates.
  • It proposes a future direction for implantable bone devices.

    • Main Results:

    • Instrumented active implants are identified as the most promising technology for future advancements.
    • A hybrid architecture combining smart instrumentation and smart coatings is essential for optimal performance.
    • Extracorporeal systems are crucial for ensuring implant controllability.

    Conclusions:

    • The next generation of implantable bone devices will likely be instrumented active implants.
    • These multifunctional smart devices will be extracorporeally controlled by clinicians.
    • Successful implementation requires a synergistic approach involving smart materials and advanced control systems.