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[Pharmacotherapy in post-stroke rehabilitation].
R Kh Lyukmanov1, A A Rimkevichus1, E V Gnedovskaya1
1Research Center of Neurology, Moscow, Russia.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|June 27, 2022
Summary
This study reviews medications for post-stroke neurorehabilitation, highlighting Mexidol
Area of Science:
- Neurology
- Pharmacology
- Rehabilitation Medicine
Background:
- Stroke is a leading cause of long-term disability.
- Neurorehabilitation aims to restore function after stroke.
- Pharmacological interventions play a role in managing post-stroke sequelae.
Purpose of the Study:
- To evaluate the efficacy of various drugs in post-stroke neurorehabilitation.
- To provide recommendations for the rational and safe use of these agents.
- To discuss the specific role of Mexidol in stroke recovery.
Main Methods:
- Review of data on botulinum toxin, muscle relaxants, SSRIs, acetylcholinesterase inhibitors, and glutamatergic modulators.
- Analysis of clinical efficacy, particularly for Mexidol.
- Emphasis on individualized, complex rehabilitation strategies.
Main Results:
- Mexidol demonstrates a polymodal effect on motor, affective, and cognitive functions.
- Long-term sequential therapy with Mexidol shows promise.
- Complex rehabilitation tailored to patient needs is recommended.
Conclusions:
- Mexidol is a promising addition to complex stroke therapy for improving function and quality of life.
- Individualized treatment tactics are crucial for effective neurorehabilitation.
- Further high-quality clinical studies are needed to confirm pharmaceutical efficacy.
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