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[Cognitive functions in late-onset psychosis].

E G Abdullina1,2, M A Savina2, G E Rupchev2

  • 1Lomonosov Moscow State University, Moscow, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|June 27, 2022
PubMed
Summary

Late-onset schizophrenia shows greater cognitive deficits than normal aging but less than early-onset schizophrenia. Cognitive dysfunction in late-onset schizophrenia may vary, requiring further research into its dynamics.

Keywords:
cognitive functionslate-onset schizophrenianeuropsychologyschizophrenia

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Science

Background:

  • Late-onset schizophrenia (LOS) and very late-onset schizophrenia-like psychosis (VLOS) present unique challenges in understanding cognitive decline.
  • Cognitive function in aging populations is a critical area of research, with implications for diagnosis and treatment.

Purpose of the Study:

  • To compare cognitive functions in LOS and VLOS with normal aging, early-onset schizophrenia (EOS), and neurodegenerative diseases.
  • To highlight the dynamics of cognitive function in LOS and discuss future research directions.

Main Methods:

  • This review synthesizes existing literature comparing cognitive profiles across different patient groups and aging.
  • Analysis focuses on cognitive deficits and their severity in various conditions.

Main Results:

  • Patients with LOS exhibit more significant cognitive deficits than normally aging individuals.
  • Cognitive impairments in LOS are less severe than those observed in EOS.
  • LOS may represent a heterogeneous condition regarding the pattern and extent of cognitive dysfunction.

Conclusions:

  • Cognitive profiles in LOS differ markedly from normal aging and EOS.
  • Further research is needed to understand the heterogeneity and dynamic changes in cognitive function within LOS.