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[Cognitive functions in late-onset psychosis].
E G Abdullina1,2, M A Savina2, G E Rupchev2
1Lomonosov Moscow State University, Moscow, Russia.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|June 27, 2022
Summary
Late-onset schizophrenia shows greater cognitive deficits than normal aging but less than early-onset schizophrenia. Cognitive dysfunction in late-onset schizophrenia may vary, requiring further research into its dynamics.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Science
Background:
- Late-onset schizophrenia (LOS) and very late-onset schizophrenia-like psychosis (VLOS) present unique challenges in understanding cognitive decline.
- Cognitive function in aging populations is a critical area of research, with implications for diagnosis and treatment.
Purpose of the Study:
- To compare cognitive functions in LOS and VLOS with normal aging, early-onset schizophrenia (EOS), and neurodegenerative diseases.
- To highlight the dynamics of cognitive function in LOS and discuss future research directions.
Main Methods:
- This review synthesizes existing literature comparing cognitive profiles across different patient groups and aging.
- Analysis focuses on cognitive deficits and their severity in various conditions.
Main Results:
- Patients with LOS exhibit more significant cognitive deficits than normally aging individuals.
- Cognitive impairments in LOS are less severe than those observed in EOS.
- LOS may represent a heterogeneous condition regarding the pattern and extent of cognitive dysfunction.
Conclusions:
- Cognitive profiles in LOS differ markedly from normal aging and EOS.
- Further research is needed to understand the heterogeneity and dynamic changes in cognitive function within LOS.
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