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Transauricular Vagus Nerve Stimulation and Electroencephalographic Assessment in Disorders of Consciousness
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Lucid Dreams Associated with Pregabalin: Implications for Clinical Practice
Meghan F Haas1, Jessica Latchman1, Ann M Guastella1
1Meghan F. Haas, DO, FACOI, Jessica Latchman, ARNP, Ann M. Guastella, ARNP, David S. Craig, PharmD, and Young D. Chang, MD, are with theDepartment of Supportive Care, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.
Journal of Pain & Palliative Care Pharmacotherapy
|June 27, 2022
Summary
This case study reports a patient with multiple myeloma experiencing lucid dreams. The lucid dreams resolved after discontinuing pregabalin, suggesting a potential link between this medication and dream alterations.
Area of Science:
- Neurology
- Pharmacology
Background:
- Multiple myeloma is a cancer of plasma cells.
- Methadone and pregabalin are commonly prescribed for pain management in cancer patients.
Observation:
- A patient with multiple myeloma developed lucid dreams during treatment.
- Initial suspicion fell on methadone, but reducing its dosage did not resolve the dreams.
Findings:
- Lucid dreams persisted despite methadone dose reduction.
- Lucid dreams resolved only after the discontinuation of pregabalin.
- This is the first reported case associating pregabalin with lucid dreams.
Implications:
- Pregabalin may induce lucid dreams in some patients.
- Clinicians should consider pregabalin as a potential cause for reported dream disturbances.
- Further research is warranted to explore the neurobiological mechanisms underlying this association.
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