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Serious reporting deficiencies exist in minimal important difference studies: current state and suggestions for
Alonso Carrasco-Labra1, Tahira Devji2, Anila Qasim2
1Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main St East, Hamilton, Ontario, Canada L8S 4L8; Center for Integrative Global Oral Health, University of Pennsylvania, School of Dental Medicine, 240 S. 40th Street, 3rd Fl East, Philadelphia, PA 19104, USA.
Reporting of minimal important difference (MID) estimates for patient-reported outcome measures (PROMs) is frequently incomplete. These deficiencies, including lack of detail on anchors and variability, undermine the credibility and optimal use of MID findings.
Area of Science:
- Health Outcomes Research
- Clinical Trial Methodology
- Psychometrics
Background:
- Minimal Important Difference (MID) estimates are crucial for interpreting patient-reported outcome measures (PROMs).
- Anchor-based methods are commonly used to derive MIDs.
- The credibility of MID estimates depends on transparent and complete reporting.
Purpose of the Study:
- To evaluate the reporting quality of anchor-based MID estimates for PROMs.
- To assess the association between reporting deficiencies and the credibility of MID estimates.
Main Methods:
- Systematic survey of primary studies estimating MIDs.
- Searched multiple databases (Medline, EMBASE, PsycINFO, etc.) up to October 2018.
- Evaluated reporting of study characteristics, PROMs, anchors, and MID estimation methods.
Main Results:
- 585 studies reported 5,324 MID estimates for 526 PROMs.
- Frequent failure to report key characteristics like scale range, variability, and sample size.
- Significant reporting issues impacting credibility included low reporting of anchor-PROM correlation (66%) and insufficient details on precision (13%) and thresholds (16%).
Conclusions:
- Incomplete reporting in the MID literature is a serious concern.
- These deficiencies threaten the optimal utilization of MID estimates.
- Improved reporting standards are needed to enhance the credibility and utility of MID findings for intervention effects.
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