Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Radiation-Induced Wavelength Shifts in Fiber Bragg Gratings Exposed to Gamma Rays and Neutrons in a Nuclear Reactor.

Sensors (Basel, Switzerland)·2025
Same author

Dose-consistent dynamic SPECT.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology·2022
Same author

Preliminary study of thermal density distribution and entropy analysis during cycling exercise stress test using infrared thermography.

Scientific reports·2022
Same author

A new cardiac phantom for dynamic SPECT.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology·2020
Same author

Performance characteristics of pressure infusors.

Technology and health care : official journal of the European Society for Engineering and Medicine·2014
Same author

Performance characteristics of pressure infusors.

Technology and health care : official journal of the European Society for Engineering and Medicine·2014

Related Experiment Video

Updated: Sep 6, 2025

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

3.8K

Anthropomorphic cardiac phantom for dynamic SPECT.

A Krakovich1, U Zaretsky2, E Gelbart3

  • 1Department of Biomedical Engineering, Tel-Aviv University, Tel-Aviv, Israel. krakovich@mail.tau.ac.il.

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
|June 27, 2022
PubMed
Summary

A new dynamic cardiac phantom was developed to validate myocardial blood flow (MBF) measurements using SPECT imaging. The phantom accurately mimics heart function and radiotracer flow, showing good agreement with expected MBF values.

Keywords:
SPECTinstrumentationmyocardial blood flow

More Related Videos

Development and Evaluation of 3D-Printed Cardiovascular Phantoms for Interventional Planning and Training
09:57

Development and Evaluation of 3D-Printed Cardiovascular Phantoms for Interventional Planning and Training

Published on: January 18, 2021

4.1K
Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph
05:32

Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph

Published on: February 21, 2025

417

Related Experiment Videos

Last Updated: Sep 6, 2025

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

3.8K
Development and Evaluation of 3D-Printed Cardiovascular Phantoms for Interventional Planning and Training
09:57

Development and Evaluation of 3D-Printed Cardiovascular Phantoms for Interventional Planning and Training

Published on: January 18, 2021

4.1K
Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph
05:32

Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph

Published on: February 21, 2025

417

Area of Science:

  • Nuclear medicine
  • Medical imaging
  • Cardiovascular imaging

Background:

  • Myocardial blood flow (MBF) measurement using SPECT systems requires robust validation.
  • Existing methods for MBF validation are limited.
  • A novel dynamic cardiac phantom was developed to address these limitations.

Purpose of the Study:

  • To develop and validate a dynamic cardiac phantom for MBF measurements in SPECT.
  • To assess the impact of radiotracer dose on MBF accuracy.
  • To evaluate the performance of SPECT systems in quantifying MBF.

Main Methods:

  • A mechanical cardiac phantom was integrated into an anthropomorphic torso.
  • Measurements were performed using a GE Discovery 530c SPECT system.
  • Dynamic SPECT experiments were conducted to validate MBF accuracy and study radiotracer dose effects.

Main Results:

  • Gamma-ray attenuation significantly impacts MBF measurements, limiting resolution.
  • Dynamic SPECT experiments showed a mean relative error of 14% for MBF accuracy.
  • MBF uncertainty did not increase significantly with reduced radiotracer doses due to temporal integration.

Conclusions:

  • A dynamic cardiac phantom was successfully developed and integrated for SPECT imaging.
  • The phantom demonstrated good agreement between SPECT-reported MBF and expected results.
  • MBF measurements remain accurate even at low radiotracer doses, indicating robustness.