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Bone composition in the distal forearm.

L Nilas, H Nørgaard, J Pødenphant

    Scandinavian Journal of Clinical and Laboratory Investigation
    |February 1, 1987
    PubMed
    Summary
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    Distal forearm bone mass measurements are superior for identifying osteoporosis compared to proximal sites. This study confirms distal measurements

    Area of Science:

    • Bone biology and osteoporosis research.

    Background:

    • Osteoporosis identification relies on accurate bone mass assessment.
    • Recent data suggest distal forearm measurements are more effective than proximal ones.

    Purpose of the Study:

    • To evaluate the accuracy of distal versus proximal bone mass measurements in the forearm for osteoporosis identification.
    • To analyze the trabecular bone fraction and its distribution in the distal forearm.

    Main Methods:

    • Obtained 16 distal forearm bone slices from necropsies.
    • Measured trabecular bone fraction (wt/wt) in 8 mm thick slices.
    • Utilized multipath single photon absorptiometry for proximal and distal bone mineral content (BMC) measurements prior to autopsy.

    Main Results:

    • Accuracy of bone measurements at proximal and distal sites was comparable (r = 0.98 and r = 0.94).

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  • Trabecular bone fraction increased towards the metaphysis, with ratios from 10% to 60% (wt/wt).
  • Bone loss rates can be estimated if bone composition is known.

    • Conclusions:

    • Distal forearm bone mass measurement is a reliable indicator for osteoporosis.
    • The trabecular bone structure in the distal forearm shows a specific distribution pattern.
    • Accurate bone composition data can aid in monitoring bone loss over time.