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Updated: Sep 6, 2025

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection
Published on: June 5, 2021
The humoral response and antibodies against SARS-CoV-2 infection
Hai Qi1,2,3,4,5,6, Bo Liu7,8,9, Xinquan Wang10,11
1Tsinghua-Peking Center for Life Sciences, Beijing, China. qihai@tsinghua.edu.cn.
Abstract:
Two and a half years into the COVID-19 pandemic, we have gained many insights into the human antibody response to the causative SARS-CoV-2 virus. In this Review, we summarize key observations of humoral immune responses in people with COVID-19, discuss key features of infection- and vaccine-induced neutralizing antibodies, and consider vaccine designs for inducing antibodies that are broadly protective against different variants of the SARS-CoV-2 virus.
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