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Related Concept Videos

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Cancer Therapies02:49

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Combination Therapies and Personalized Medicine02:50

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Tumor Progression

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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Updated: Sep 6, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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Interventional oncology update.

Alex Newbury1, Chantal Ferguson1, Daniel Alvarez Valero1

  • 1UMass Memorial Medical Center, Worcester, MA, USA.

European Journal of Radiology Open
|June 28, 2022
PubMed
Summary
This summary is machine-generated.

Interventional Oncology (IO) advances cancer diagnosis and treatment by integrating interventional radiology with clinical oncology. This review focuses on four key IO topics poised to transform future cancer care.

Keywords:
Artificial intelligenceBreast ablationImmune checkpoint inhibitorsInterventional oncologyProstate ablation

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Area of Science:

  • Interventional Radiology
  • Oncology
  • Cancer Treatment

Background:

  • Interventional Oncology (IO) is an emerging subspecialty.
  • It bridges diagnostic radiology and clinical oncology.
  • Recent advancements necessitate focused reviews.

Purpose of the Study:

  • To review significant advancements in Interventional Oncology.
  • To highlight four specific topics with transformative potential.
  • To provide an outlook on the future of cancer management.

Main Methods:

  • Literature review of recent Interventional Oncology advancements.
  • Selection of four high-impact topics for detailed discussion.
  • Synthesis of current knowledge and future trends.

Main Results:

  • Identification of four key areas within IO.
  • Discussion of the potential impact of these advancements on cancer treatment.
  • Analysis of the integration of IO within the multidisciplinary oncology team.

Conclusions:

  • Interventional Oncology is rapidly evolving.
  • Selected IO advancements show promise for significantly altering cancer treatment paradigms.
  • Continued research and integration are crucial for optimizing patient outcomes.