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A Systematic Review of Arterial Dissections in COVID-19 Patients
Betsy Abraham1, Sherman David Mathew2, Kannan Sridharan3
1Department of Intensive Care, Salmaniya Medical Complex, Manama, Kingdom of Bahrain.
Insights
This study analyzes arterial dissections in COVID-19 patients, investigating theories of endothelial dysfunction and hyperinflammation. The exact incidence remains unknown, with only case reports available.
Area of Science:
- Cardiovascular Medicine
- Infectious Diseases
- Vascular Surgery
Background:
- COVID-19 can manifest as multiorgan dysfunction, including arterial dissections.
- The precise incidence of arterial dissection in COVID-19 patients is not well-established.
- Existing literature primarily consists of case reports and series.
Conclusions:
- Arterial dissection is a recognized, albeit rare, complication of COVID-19.
- Further research and larger cohort studies are needed to determine the exact incidence and risk factors.
- Understanding the link between COVID-19, hyperinflammation, and endothelial dysfunction is crucial for managing these vascular complications.
Introduction:
COVID-19 is often seen presenting with a myriad of signs and symptoms of multiorgan dysfunction including arterial dissection.
Methods:
Various theories have been proposed such as endothelial dysfunction triggered by hyperinflammatory response that results in rupture of atherosclerotic plaque and subsequent dissection.
Results:
However, the exact incidence is unknown and only case reports and case series have been published till date.
Conclusion:
Here we carried out a systematic analysis of published case reports/series related to dissection of the aorta, coronary, cerebral, vertebral, cervical, renal, and splanchnic arteries.
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