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Intestinal absorption studies in Fasciolopsis buski infection
The Southeast Asian Journal of Tropical Medicine and Public Health
|December 1, 1986
Summary
Fasciola buski infection slightly impairs vitamin B12 absorption and serum levels in patients. Carbohydrate, fat, protein absorption, and folate levels remained unaffected by the parasite.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Nutritional Science
Background:
- Intestinal parasites can impact nutrient absorption and host health.
- Fasciola buski is a liver fluke that infects the small intestine.
Purpose of the Study:
- To investigate the effects of Fasciola buski infection on intestinal absorption and nutrient levels.
- To assess potential malabsorption of carbohydrates, fats, proteins, and vitamin B12.
Main Methods:
- Studied 10 patients infected with Fasciola buski.
- Assessed intestinal absorption of macronutrients and vitamin B12.
- Measured serum vitamin B12 and red blood cell folate levels.
- Performed jejunal biopsy for histological examination.
Main Results:
- No significant malabsorption of carbohydrates, fats, or proteins was observed.
- Vitamin B12 absorption was reduced in 80% of patients.
- Serum vitamin B12 levels were low in 44% of patients.
- Serum and red blood cell folate levels were normal.
- Jejunal histology was normal in most patients.
Conclusions:
- Fasciola buski infection may lead to subclinical vitamin B12 deficiency.
- The parasite appears to primarily affect vitamin B12 absorption.
- Further research is needed to understand the mechanisms of vitamin B12 malabsorption in F. buski infections.