Related Experiment Video
Updated: Sep 6, 2025

Identification of Mycobacterium Species by DNA Microarray Chip Method
Published on: June 24, 2025
Diagnosing and treating Mycobacterium kansasii.
Randy R Moore1, Douglas Holder, Sarah Earnest
1Randy R. Moore practices in family medicine at Wellness Pointe Family Health in Longview, Tex., and is a major in the Texas Army National Guard. Douglas Holder is a radiologist at Red River Valley Radiology Associates and Open Imaging of Longview, Tex. Sarah Earnest is a family nurse practitioner at Special Health Resources in Longview, Tex. The authors have disclosed no potential conflicts of interest, financial or otherwise.
An 18-year-old patient developed Mycobacterium kansasii lung infection, presenting with shortness of breath and a cavitary lesion. Early diagnosis via sputum culture led to effective antimycobacterial treatment.
Area of Science:
- Pulmonology
- Infectious Diseases
- Microbiology
Background:
- Mycobacterium kansasii is an atypical mycobacterium that can cause pulmonary disease, particularly in individuals with underlying lung conditions.
- While typically associated with chronic lung disease, M. kansasii can also affect immunocompetent individuals.
Purpose of the Study:
- To report a case of Mycobacterium kansasii infection in an 18-year-old immunocompetent patient.
- To highlight the clinical presentation and diagnostic challenges of M. kansasii pulmonary disease.
Main Methods:
- Case report of an 18-year-old patient with respiratory symptoms.
- Radiographic evaluation revealing a cavitary lung lesion.
- Sputum smear and culture for mycobacterial identification.
Main Results:
- Initial sputum smears were negative for acid-fast bacilli.
- Sputum cultures eventually grew Mycobacterium kansasii after two weeks.
- The patient was initiated on an appropriate antimycobacterial regimen.
Conclusions:
- Mycobacterium kansasii should be considered in the differential diagnosis of pulmonary infections, even in immunocompetent young patients.
- Prompt microbiological investigation, including culture, is crucial for diagnosing M. kansasii infections.
- Timely initiation of antimycobacterial therapy is essential for successful treatment outcomes.
Related Concept Videos
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:

