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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Direct-acting cholinergic agonists have many therapeutic uses in various medical fields. Choline esters, including acetylcholine, have limited clinical utility due to their non-selectivity and short duration of action. Still, acetylcholine and carbachol are applied topically during ophthalmologic surgery to induce miosis. Pilocarpine, a muscarinic and ganglionic stimulator, effectively treats open-angle glaucoma and alleviates xerostomia and dry mouth caused by radiotherapy or Sjögren...
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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Updated: Sep 6, 2025

Iris Fixation via External Pentagram Suturing
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Ocular Rigidity and Current Therapy.

Diane N Sayah1,2, Mark R Lesk1,3,4

  • 1Maisonneuve-Rosemont Hospital Research Center, Montreal, Canada.

Current Eye Research
|June 28, 2022
PubMed
Summary
This summary is machine-generated.

Ocular rigidity (OR) is a key eye biomechanical property. Understanding OR and developing therapies targeting it offers new hope for treating glaucoma and myopia.

Keywords:
Ocular rigidityglaucomamyopiascleral cross-linkingtherapy

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Ocular Biomechanics

Background:

  • Ocular rigidity (OR) reflects the corneoscleral shell's material and geometric properties.
  • OR plays a crucial role in ocular health and disease.
  • Understanding OR is vital for developing effective treatments for eye conditions.

Purpose of the Study:

  • To review the role of ocular rigidity in eye diseases.
  • To explore potential therapies targeting ocular rigidity.
  • To examine the application of these therapies in glaucoma and myopia.

Main Methods:

  • Literature search and review.
  • Analysis of biomechanical modeling and scleral properties.
  • Evaluation of novel ocular rigidity measurement and imaging techniques.

Main Results:

  • Biomechanical modeling and scleral constituent understanding provide key insights.
  • Non-invasive OR measurement and advanced imaging facilitate clinical studies.
  • Improved understanding of OR in disease progression is advancing research.

Conclusions:

  • Enhanced understanding of ocular rigidity is refining therapeutic strategies.
  • Targeting scleral biomechanical properties offers potential for treating glaucoma and myopia.
  • Continued research into ocular rigidity determinants will drive innovation in eye care.