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Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
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Chronic thrombosis of bioprostheses: Diagnosis and management

Jasmin H Shahinian1, Vincent Chan2, Sorin V Pislaru3

  • 1Department of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Canada; Department of Cardiovascular Surgery, University Heart Center Freiburg, Bad Krozingen, Germany.

Progress in Cardiovascular Diseases
|June 28, 2022
PubMed

Insights

Bioprosthetic valve thrombosis is a growing concern, increasing despite these valves not requiring anticoagulation. This review covers diagnosis, treatment, and management strategies for this condition.

Area of Science:

  • Cardiology
  • Biomedical Engineering

Background:

  • Acquired valvular heart disease leads to significant mortality and morbidity.
  • Bioprosthetic valves are used in up to 90% of over 100,000 annual US valve operations.
  • Prosthetic valve thrombosis incidence is rising, despite bioprosthetic valves not needing lifelong anticoagulation.

Purpose of the Study:

  • To review the current diagnostic methods for bioprosthetic valve thrombosis.
  • To outline treatment modalities for bioprosthetic valve thrombosis.
  • To discuss the management of bioprosthetic valve thrombosis.

Main Methods:

  • Literature review of current diagnostic techniques.
  • Analysis of established and emerging treatment options.
  • Synthesis of best practices for patient management.

Main Results:

  • Bioprosthetic valve thrombosis presents a significant clinical challenge.
  • Early diagnosis and appropriate management are crucial for patient outcomes.
  • Treatment strategies vary based on clinical presentation and valve location.

Conclusions:

  • Bioprosthetic valve thrombosis requires careful monitoring and timely intervention.
  • Further research is needed to optimize diagnostic and therapeutic approaches.
  • Effective management can mitigate the risks associated with bioprosthetic valve thrombosis.

Keywords:
AnticoagulationBioprosthetic thrombosisBioprosthetic valve

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