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Increased Mortality in Patients With Acutely Decompensated Heart Failure During the COVID-19 Pandemic in Toronto,
Tayler A Buchan1, Lakshmi Kugathasan1, Jeremy Kobulnik1,2
1Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Insights
During COVID-19, fewer acute decompensated heart failure patients sought care, leading to a 66% rise in in-hospital mortality. Improved public health messaging is crucial for chronic condition management during pandemics.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- The COVID-19 pandemic led to reduced healthcare-seeking for non-COVID-19 conditions.
- Previous reports indicated fewer emergency department visits and hospitalizations for acute decompensated heart failure (ADHF) in 2020 compared to 2019.
- The impact of these trends on ADHF patient outcomes remained unclear.
Purpose of the Study:
- To investigate the consequences of reduced healthcare utilization on ADHF patient morbidity and mortality during the COVID-19 pandemic.
- To compare outcomes for ADHF patients presenting in early 2020 versus 2019.
Main Methods:
- A comparative study of consecutive ADHF patients across three Toronto academic medical centers.
- Data collected from March 1 to September 28, 2020, and compared to the same period in 2019.
- Multivariate logistic regression used to analyze differences in hospitalization, 30-day readmission, and in-hospital mortality.
Main Results:
- Fewer ADHF patients presented to the hospital in 2020 compared to 2019.
- Hospital admission rates for presenting ADHF patients did not differ between the two periods.
- Admitted ADHF patients in 2020 showed a higher ICU admission rate and a 66% relative increase in in-hospital mortality compared to 2019.
Conclusions:
- The COVID-19 pandemic was associated with increased in-hospital mortality for acute decompensated heart failure patients.
- Patients with chronic conditions like heart failure may require enhanced public health messaging to encourage timely hospital visits.
- Proactive communication strategies are essential to ensure continuity of care for chronic diseases during public health crises.
Background:
Coronavirus disease 2019 (COVID-19) has resulted in a reduction in patients seeking timely consultation for illnesses that are not related to COVID-19. Previously, we reported a decline in the number of emergency department (ED) visits and hospitalizations for acute decompensated heart failure (ADHF) during the 2020 COVID-19 pandemic vs that in 2019. We aimed to determine the consequences of these early trends on ADHF-patient morbidity and mortality.
Methods:
We compared consecutive patients presenting with ADHF to 3 academic medical centres in Toronto, Canada from March 1-September 28, 2020, vs those from the same time period in 2019. We used multivariate logistic regression models to evaluate whether the odds of hospitalization after presenting to the ED, recurrent ED visits or readmission within 30 days, and in-hospital all-cause mortality differed by timeframe.
Results:
We observed that, during the COVID-19 pandemic, a lower total number of patients presented to the hospital with ADHF, vs that in 2019. Despite this difference, the probability of being admitted to the hospital did not differ for patients seen in 2020 vs 2019. Among ADHF patients admitted to the hospital, however, we observed a significantly higher proportion being admitted to the intensive care unit, and a relative 66% increase in in-hospital mortality during the 2020 COVID-19 era, compared to that in 2019.
Conclusions:
Our findings suggest that improved messaging may be needed for patients living with chronic health conditions, including HF, during the pandemic, to educate and encourage them to present to hospital services when in need.
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