Related Experiment Video
Updated: Sep 6, 2025

A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique
Published on: April 26, 2015
Prolonged Resuscitation with Multiple Defibrillations; a Case Report
Shaghayegh Rahmani1, Elham Mokhtari Amirmajdi2, Rana Kolahi Ahari3
1Innovated Medical Research Center, Faculty of Medicine, Mashhad Branch, Islamic Azad University, Mashhad, Iran.
Insights
Deciding when to stop cardiopulmonary resuscitation (CPR) is unclear, especially for shockable rhythms. This case highlights the challenges in determining resuscitation endpoints despite potential for good outcomes after prolonged efforts.
Area of Science:
- Emergency Medicine
- Cardiology
- Critical Care Medicine
Background:
- American Heart Association (AHA) guidelines provide standardized cardiopulmonary resuscitation (CPR) protocols.
- Clear recommendations for terminating resuscitation, particularly in shockable rhythms, are lacking.
- Evidence regarding optimal CPR duration and defibrillation attempts remains insufficient.
Observation:
- A challenging case of cardiac arrest requiring emergency room CPR is presented.
- Difficulties were encountered in deciding the appropriate endpoint for resuscitation efforts.
- The patient received CPR in the emergency room setting.
Findings:
- The abstract does not contain specific findings, but rather describes a clinical scenario.
- It highlights the ambiguity in current guidelines regarding resuscitation termination criteria.
- The case underscores the complexity of decision-making in prolonged CPR.
Implications:
- Further research is needed to establish clear criteria for terminating resuscitation in cardiac arrest.
- Understanding the potential for good neurological outcomes after prolonged CPR is crucial.
- Clinical practice requires better guidance on managing resuscitation endpoints in challenging cases.
Abstract:
Although American Heart Association Guidelines (AHA) are practical and standardized in many aspects of cardiopulmonary resuscitation (CPR) performance, recommendations on when to terminate resuscitation are not fully understood and clear. There is not enough evidence about how long we can continue CPR in shockable rhythms and how many shocks can be delivered to patients, and if there is an end point for it or not. This issue is more challenging when we read papers published on survival rates and good functional and neurological outcomes after prolonged CPRs. Here, we demonstrate a case of cardiac arrest receiving CPR in the emergency room, for whom it was hard and challenging to make a decision on when to terminate the resuscitation attempts.
Related Concept Videos
Cardiopulmonary Resuscitation III: AED Use
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiopulmonary Resuscitation I: Adult
Cardiomyopathy II: Dilated Cardiomyopathy
Dysrhythmias VI: Management of Dysrhythmias

