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Updated: Oct 2, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Nivolumab-ipilimumab in renal cell carcinoma metastatic to the bones: A case report
Marilena Di Napoli1, Carmela Pisano2, Sergio Venanzio Setola3
1Department of Urogynecology, National Cancer Institute, Pascale Foundation, Naples, Italy. m.dinapoli@istitutotumori.na.it.
Abstract:
In the last recent years, the introduction in the clinical setting of treatment combinations having immune checkpoint inhibitors as the backbone has dramatically improved the outcomes of patients suffering from advanced/metastatic renal cell carcinoma (RCC). Here we report the clinical course of a patient with a rapid and bulky bone recurrence of RCC after nephrectomy, experiencing long-term benefit from nivolumab-ipilimumab administered as first-line treatment.
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