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Agreement between Two Swept-Source Optical Coherence Tomography Biometers and a Partial Coherence Interferometer.

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This study compared ocular biometrics from three devices, finding good agreement for axial length but poor agreement for astigmatism measurements. Intraocular lens power predictions were not interchangeable between devices.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Optometry

Background:

  • Accurate ocular biometrics are crucial for refractive surgery and intraocular lens (IOL) power calculation.
  • Several devices are available for measuring parameters like keratometry, anterior chamber depth, and axial length.
  • Evaluating the agreement between these devices is essential for consistent clinical practice.

Purpose of the Study:

  • To assess the agreement of ocular biometric measurements between the ANTERION, OA-2000, and IOLMaster 500 devices.
  • To compare the predicted intraocular lens power using different formulas across the three devices.

Main Methods:

  • Fifty-one eyes were measured using ANTERION, OA-2000, and IOLMaster 500 for flat K, steep K, astigmatism components (J0, J45), anterior chamber depth, and axial length.
  • Statistical analysis included repeated measures ANOVA, Pearson correlation, and Bland-Altman plots to evaluate agreement.
  • IOL power was predicted using SRK/T, Haigis, Barrett Universal II, and Kane formulas.

Main Results:

  • ANTERION measured flatter keratometry values compared to other devices, though agreement for flat K and steep K was good between ANTERION and OA-2000, and OA-2000 and IOLMaster 500.
  • Agreement for astigmatism components (J0, J45) was poor across all devices.
  • Anterior chamber depth showed good agreement between ANTERION and OA-2000; axial length demonstrated high agreement among all three devices.
  • Predicted IOL powers were not interchangeable between the devices, irrespective of the formula used.

Conclusions:

  • Significant differences exist in ocular biometrics measured by ANTERION compared to OA-2000 and IOLMaster 500.
  • Only axial length measurements showed good agreement across all three devices.
  • The lack of agreement in keratometry and astigmatism, and the non-interchangeability of IOL power predictions, highlight potential clinical implications.