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Radiomics in Abdominopelvic Solid-Organ Oncologic Imaging: Current Status
Xiaoyang Liu1, Mohamed G Elbanan2, Antonio Luna3
1Joint Department of Medical Imaging, Division of Abdominal Imaging, University Health Network, University of Toronto, ON, Canada.
AJR. American Journal of Roentgenology
|June 29, 2022
Summary
Radiomics, extracting quantitative imaging features, shows promise for abdominopelvic cancers. However, more robust evidence is needed for widespread clinical use due to methodological inconsistencies.
Area of Science:
- Radiology
- Medical Imaging
- Oncology
Background:
- Radiomics extracts high-throughput quantitative imaging features, serving as noninvasive biomarkers beyond visual interpretation.
- These quantitative imaging biomarkers offer potential for enhanced cancer assessment.
Purpose of the Study:
- To review the radiomics pipeline steps and current evidence for its application in abdominopelvic solid-organ cancers.
- To explore radiomics in diagnosis, subtype determination, treatment response, and outcome prediction for various cancers.
Main Methods:
- Literature review focusing on systematic reviews, meta-analyses, and large multicenter studies.
- Analysis of radiomics applications in hepatobiliary, pancreatic, renal, prostate, gynecologic, and adrenal cancers.
Main Results:
- Radiomics shows potential applications across various abdominopelvic cancers.
- Identified limitations include methodological heterogeneity, small sample sizes, lack of external validation, and absence of prospective designs.
Conclusions:
- Radiomics research provides a foundation for further investigation.
- Stronger, validated evidence is required before widespread clinical adoption of radiomics models.
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