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Effect of CoolSense and EMLA Cream on Pain During Intravenous Cannulation in Pediatric Population: A Randomized,

Pratibha Alice Xess1, Rashi Sarna1, Sameer Sethi1

  • 1Department of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

Indian Journal of Pediatrics
|June 29, 2022
PubMed

Insights

CoolSense significantly reduced pain during intravenous cannulation in children compared to EMLA cream. This rapid and effective method offers better analgesia for pediatric venous cannulation.

Area of Science:

  • Pediatric Anesthesiology
  • Pain Management
  • Dermatology

Background:

  • Intravenous cannulation is a common procedure in pediatric care.
  • Pain and anxiety are significant concerns during pediatric intravenous cannulation.
  • Topical anesthetics like EMLA cream are often used but have limitations.

Purpose of the Study:

  • To compare the efficacy of CoolSense versus EMLA cream for pain reduction during pediatric intravenous cannulation.
  • To evaluate secondary outcomes including anxiety, procedural success, and patient/parent satisfaction.

Main Methods:

  • 140 pediatric patients (ASA I/II, 6-12 years) were randomized into two groups.
  • Group I received CoolSense pretreatment; Group II received EMLA cream pretreatment.
  • Pain scores, anxiety levels, procedural success, and adverse events were assessed.

Main Results:

  • CoolSense demonstrated a significantly greater reduction in pain scores compared to EMLA cream (p=0.001).
  • The CoolSense group showed a significant decrease in pre- and post-procedural anxiety levels (p=0.003).
  • CoolSense required a significantly shorter application duration than EMLA cream.

Conclusions:

  • CoolSense is more efficacious than EMLA cream in alleviating pain during pediatric intravenous cannulation.
  • CoolSense offers a simple, rapid, and effective analgesic option for venous cannulation in children.
Abstract

Keywords:
CoolSenseEMLAIntravenous cannulationPediatrics

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