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Updated: Aug 15, 2026

Optimized Fibrin Gel Bead Assay for the Study of Angiogenesis
Published on: April 29, 2007
[Aggregation of fibrinogen molecules in a solution]
Abstract:
Fibrinogen is found to be able to produce highly molecular aggregates in solution. Its maximal quantity aggregates at the temperature of 4 degrees C. The pH dependence of fibrinogen aggregates production is shown. Highly molecular aggregates of fibrinogen are found to be produced mainly due to hydrogen bonds. Electron-microphotography of aggregated fibrinogen is presented. Complementary molecular loci responsible for the formation of ordered aggregates are discussed from the standpoint of their significance in the fibrin polymerization.
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