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Related Concept Videos

Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Evolutionary Relationships through Genome Comparisons02:54

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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Next-generation Sequencing03:00

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The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
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Genome Annotation and Assembly03:36

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The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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Synthetic Biology02:55

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Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
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Human Genetics01:28

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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
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Related Experiment Video

Updated: Sep 6, 2025

A Virtual Machine Platform for Non-Computer Professionals for Using Deep Learning to Classify Biological Sequences of Metagenomic Data
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Genomics enters the deep learning era.

Etienne Routhier1, Julien Mozziconacci2

  • 1LPTMC, Sorbonne Université, Paris, France.

Peerj
|June 30, 2022
PubMed
Summary
This summary is machine-generated.

Deep learning is revolutionizing bioinformatics with deep genomics, analyzing vast biological sequence data. This technology enhances genome annotation, identifies function determinants, and enables synthetic sequence generation.

Keywords:
BioinformaticsDeep learningEpigenomicsGeneticsGenomicsMetagenomicsNeural networksPersonalized medecineReviewSynthetic genomes

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Area of Science:

  • Bioinformatics
  • Genomics
  • Machine Learning

Background:

  • The exponential growth of biological sequence data necessitates advanced analytical methods.
  • Deep learning (DL) techniques, successful in computer vision and NLP, offer powerful new tools for bioinformatics.

Approach:

  • This review explores the transformative impact of applying DL to genomic sequences, termed deep genomics.
  • We focus on DL's applications in functional genome annotation, deciphering sequence-function relationships, and generating synthetic genomic data.

Key Points:

  • Deep genomics facilitates high-throughput functional annotation of genomes.
  • DL models can elucidate the sequence determinants underlying genome functions.
  • The application of DL extends to the creation of novel, synthetic genomic sequences.

Conclusions:

  • Deep learning represents a paradigm shift in genomic data analysis.
  • Deep genomics is poised to accelerate discoveries in functional genomics and synthetic biology.