Impact of Short-Term Heart Rate Variability in Patients with STEMI Treated by Delayed versus Immediate Stent in...

Area of Science:

• Cardiology
• Interventional Cardiology
• Cardiac Electrophysiology

Background:

• ST-segment elevated myocardial infarction (STEMI) management often involves primary percutaneous coronary intervention (pPCI).
• The choice between immediate stent (IS) and delayed stent (DS) strategies impacts outcomes.
• Limited data exists on electrocardiac activity and autonomic function post-pPCI based on stent timing.

Purpose of the Study:

• To investigate the effects of short-term heart rate variability (HRV) in STEMI patients treated with IS versus DS strategies.
• To compare cardiac electrical stability and autonomic nerve function between IS and DS groups post-pPCI.

Main Methods:

• A cohort of 178 STEMI patients were analyzed, divided into IS (124 patients) and DS (54 patients) groups.
• Data collected included heart rate, premature ventricular contractions (PVCs), left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVED), and HRV indexes.
• Statistical comparisons were made between the IS and DS groups.

Main Results:

• The DS group exhibited lower numbers and percentages of PVCs, indicating improved cardiac electrical stability.
• Higher high-frequency (HF) and standard deviation of all NN (SDNN) intervals were observed in the DS group, suggesting better short-term autonomic function.
• No significant differences in LVED or LVEF were found between the IS and DS groups.

Conclusions:

• The DS strategy in pPCI for STEMI patients demonstrates advantages in postoperative cardiac electrical stability and short-term cardiac autonomic nerve function.
• The DS strategy did not show a significant difference in short-term cardiac function compared to the IS strategy.
• These findings suggest that the timing of stent placement can influence electrophysiological and autonomic recovery post-STEMI.