Types of periocular wrinkles based on anatomical and contractile characteristics of participating periocular muscles:...

Clinical classification methods for periocular wrinkles based on participating muscle behavior are lacking, and traditional treatment lacks detailed and individualized methods.

This study aimed to propose a modified classification system and individualized treatment for periocular wrinkles based on the participating muscles.

Periocular wrinkles were classified into types I.I, I.II, I.III, II, and III. A personalized treatment pattern with a multipoint, low-dose technique was developed based on wrinkle classification and severity. Standard photographs were taken and assessments made at follow-up to evaluate wrinkle severity.

Wrinkle severity was reduced at 1 and 3 months after periorbital botulinum toxin injection, and no serious adverse events were recorded.

Periorbital wrinkles were classified according to participating muscles. The modified injection pattern was individualized, effective, and safe for the treatment of periorbital wrinkles.