Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Electrocardiogram

Electrocardiogram

An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...

Dysrhythmias III: Characteristics of Dysrhythmias

Dysrhythmias III: Characteristics of Dysrhythmias

Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per...

Electrocardiogram Fundamentals

Electrocardiogram Fundamentals

Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...

Cardiomyopathy IV: Restrictive Cardiomyopathy

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Flourishing in individuals undergoing maintenance hemodialysis in Shanghai: a Latent Profile Analysis.

Frontiers in psychology·2026

Same author

Association between homocysteine level and unexplained recurrent pregnancy loss: a meta-analysis.

Frontiers in endocrinology·2026

Same author

Barriers and Facilitators to Physician-Patient Communication in Chinese Tertiary Hospitals From the Perspectives of Hospital-Based Physicians and Patient Relations Coordinators: Qualitative Study.

Interactive journal of medical research·2026

Same author

Omega-3 fatty acids and cardiovascular risk-related metabolic markers in diverse populations: a meta-analysis of randomized trials.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2026

Same author

Effect of Vitamin D Supplementation on Metabolic Parameters in Patients with Metabolic-Associated Fatty Liver Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

The Journal of nutrition·2026

Same author

Physicians' perceptions of how digital-intelligent medical technology reshapes job characteristics: a qualitative study.

BMC health services research·2025

Search research articles

Related Experiment Video

Updated: Sep 6, 2025

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

The De Winter-like electrocardiogram pattern associated with multi-vessel disease.

Chunfang Wang¹, Hongli Yan¹, Jian Wang¹

¹Department of Cardiology, Binzhou Medical University Hospital, Binzhou City, China.

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

|June 30, 2022

Summary

The de Winter ECG pattern, linked to Left Anterior Descending artery occlusion, was observed in a patient with multivessel coronary artery disease. This case highlights the pattern

Keywords:

de Winter ECG pattern multi-vessel disease

More Related Videos

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

Related Experiment Videos

Last Updated: Sep 6, 2025

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

Area of Science:

Cardiology
Electrocardiography
Interventional Cardiology

Background:

The de Winter electrocardiogram (ECG) pattern is characterized by specific ST-segment and T-wave abnormalities.
This pattern has been historically associated with acute occlusion of the Left Anterior Descending (LAD) artery.

Observation:

A case study involving a patient presenting with chest pain and the de Winter ECG pattern.
The patient's 12-lead ECG exhibited upsloping ST-segment depression in anterior leads (V2-V6), tall symmetrical T waves in V2-V4, J point elevation in aVR, and ST depression in lateral leads.
The ECG findings were consistent with the de Winter pattern.

Findings:

Coronary angiography revealed significant stenosis in the LAD (60-80%) and Right Coronary Artery (RCA) (50-60% ostial, 90% mid-segment).
The patient had multivessel coronary artery disease, not solely LAD occlusion.
Percutaneous coronary intervention with drug-eluting stents was successfully performed on the RCA lesions.

Implications:

The de Winter ECG pattern may indicate multivessel coronary artery disease, extending beyond isolated LAD occlusion.
This case underscores the importance of comprehensive ECG interpretation in patients with acute coronary syndromes.
Recognition of this pattern can guide timely diagnostic and therapeutic interventions in complex coronary artery disease scenarios.