Related Experiment Video
Updated: Sep 6, 2025

08:58
Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device
Published on: December 25, 2015
16.2K
A double-step emulsification device for direct generation of double emulsions
Yu-Kai Lai1,2, Adam S Opalski1, Piotr Garstecki1
1Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland. jguzowski@ichf.edu.pl.
Soft Matter
|June 30, 2022
Summary
This study introduces a new double-step microfluidic method for creating multi-core double emulsions. The technique allows for precise control over the number of inner cores within shell droplets.
Area of Science:
- Microfluidics
- Emulsion Science
- Materials Science
Background:
- Microfluidic step emulsification is effective for monodisperse single emulsions.
- Generating double emulsions with multiple cores remains a significant challenge in microfluidics.
Purpose of the Study:
- To develop a novel double-step emulsification method for direct generation of multi-core double emulsions.
- To provide a predictive model for controlling the number of cores in double emulsions.
- To explore the potential for high-throughput production of tailored double emulsions.
Main Methods:
- Utilized a novel double-step microfluidic device.
- Investigated the formation mechanism of multi-core double emulsions.
- Developed a predictive model for core number determination.
Main Results:
- Successfully generated multi-core double emulsions with controllable core numbers.
- Observed that core passage through the shell neck delays pinch-off, influencing double emulsion formation.
- Demonstrated the creation of large, tightly packed droplet clusters with tunable core counts.
Conclusions:
- The novel double-step method enables precise control over multi-core double emulsion generation.
- The findings offer a pathway for producing complex emulsions with tailored structures.
- The system shows promise for upscaling to high-throughput applications.

