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Updated: Sep 6, 2025

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

Neurophysiology during movement disorder surgery.

Jay L Shils¹, Jeffrey E Arle², Andres Gonzalez³

¹Department of Anesthesiology, Rush University Medical Center, Chicago, IL, United States.

Handbook of Clinical Neurology

|June 30, 2022

Summary

This summary is machine-generated.

Intraoperative neurophysiology, particularly microelectrode recording, is essential for accurate targeting during deep brain stimulation surgery for movement disorders. This method confirms electrode placement in deep brain targets, ensuring surgical success.

Keywords:

Micro-electrode recording Microdrive Neurophysiologic localization Oscillations Single cells Somatotopic

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Last Updated: Sep 6, 2025

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Published on: March 8, 2015

Area of Science:

Neurosurgery
Neurophysiology
Neurology

Background:

Stereotactic procedures for movement disorders require precise targeting of deep brain structures.
Challenges include small target size, poor visualization, and the physiological nature of targets.
Traditional monitoring is evolving towards integral roles in surgical procedures.

Purpose of the Study:

To review the role of intraoperative neurophysiology in stereotactic neurosurgery.
To highlight the necessity of physiological confirmation for deep brain targets.
To discuss microelectrode recording as a key neurophysiologic monitoring method.

Main Methods:

Review of neurophysiologic monitoring techniques in stereotactic surgery.
Focus on microelectrode recording (MER) during deep brain stimulation (DBS) electrode placement.
Discussion of the integration of physiology with imaging and surgical techniques.

Main Results:

Intraoperative neurophysiology is crucial for confirming accurate anatomic targeting in deep brain procedures.
Microelectrode recording provides essential physiological feedback for electrode placement.
Despite advancements in imaging, physiological confirmation remains necessary for deep brain targets.

Conclusions:

Microelectrode recording is a commonly employed and necessary neurophysiologic monitoring method in stereotactic procedures.
Intraoperative neurophysiology has transitioned from monitoring to an integral component of surgical success.
Accurate targeting in deep brain stimulation relies on a combination of imaging and physiological data.