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Updated: Sep 6, 2025

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
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Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates

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Genome-Edited T Cell Therapies

Giorgio Ottaviano1, Waseem Qasim1

  • 1Infection, Immunity & Inflammation Department, UCL Great Ormond Street Institute of Child Health, University College London Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.

Hematology/Oncology Clinics of North America
|June 30, 2022
PubMed

Keywords:
Base editorCRISPR/Cas9Chimeric antigen receptorCytidine deaminationGenome editingT cell therapies

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