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Updated: Sep 6, 2025

Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
Published on: February 14, 2018
Clinical utility of antifungal susceptibility testing
Todd P McCarty1, Paul M Luethy2, John W Baddley3
1Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Abstract:
Invasive fungal diseases cause significant morbidity and mortality, in particular affecting immunocompromised patients. Resistant organisms are of increasing importance, yet there are many notable differences in the ability to both perform and interpret antifungal susceptibility testing compared with bacteria. In this review, we will highlight the strengths and limitations of resistance data of pathogenic yeasts and moulds that may be used to guide treatment and predict clinical outcomes.
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