Multispectral truncated-correlation photothermal coherence tomography imaging modality for detection of early stage
Elnaz Baradaran Shokouhi1,2, Robert Welch1,2, Koneswaran Sivagurunathan1,2
1Center for Advanced Diffusion-Wave and Photoacoustic Technologies, Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, M5S 3G8, Canada.
Abstract:
One of the major oral health conditions worldwide is dental caries. Light-absorption-based thermophotonic diagnostic imaging is well positioned for this challenge thanks to its speed, safety, and high molecular contrast advantages. In this work, a multispectral (MS) truncated-correlation photothermal coherence tomography (TC-PCT) imaging modality is introduced for the detection of bacterial-induced dental caries. MS TC-PCT provided thorough information about optimal lesion contrast and type of dental defects such as caries in teeth. The experimental results were validated using micro-computed tomography (µCT) including quantitative lesion depth profiles at wavelengths in the 675-700 nm range. MS TC-PCT gives rise to hard-tissue biomedical diagnostic applications such as bone and dental imaging.
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