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Celiac Disease Masquerading as Arthralgia.

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|July 1, 2022
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Summary

Celiac disease, an immune disorder from gluten, often causes digestive issues but can manifest unusually. This review explores rare symptoms like joint pain as the only sign, emphasizing early diagnosis for better outcomes.

Keywords:
anemiaarthralgiaatypical presentation of celiac diseaseiron deficiency anaemianon classical celiac disease

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Area of Science:

  • Gastroenterology
  • Immunology
  • Rheumatology

Background:

  • Celiac disease is an immune-mediated condition triggered by gluten ingestion.
  • It typically presents with gastrointestinal symptoms but has a wide spectrum of clinical manifestations.
  • Atypical presentations are increasingly recognized, impacting various organ systems.

Observation:

  • While gastrointestinal symptoms are common, celiac disease can manifest with non-classical signs.
  • These include anemia, arthritis, infertility, and neurological disorders.
  • Arthralgia (joint pain) as the sole presenting symptom of celiac disease is exceptionally rare.

Findings:

  • The broad clinical spectrum of celiac disease necessitates considering it even with atypical symptoms.
  • Recognizing these diverse presentations is crucial for timely diagnosis.
  • Prompt diagnosis and management are vital for preventing long-term complications.

Implications:

  • Highlighting rare presentations like isolated arthralgia expands the diagnostic considerations for celiac disease.
  • Increased awareness among clinicians can lead to earlier identification of celiac disease.
  • Effective management of celiac disease mitigates associated risks and improves patient prognosis.