Persistent Coronavirus Disease 2019 Headache Relieved with Sphenopalatine Ganglion Block

Danielle Levin1, Martin Acquadro1, Joseph Cerasuolo1

  • 1Department of Anaesthesia, St. Elizabeth's Medical Center, Brighton, Boston, USA.

Insights

A persistent headache following coronavirus disease 2019 (COVID-19) infection was successfully treated. A single transnasal sphenopalatine ganglion block completely resolved the patient's debilitating 5-month headache.

Area of Science:

  • Neurology
  • Pain Medicine
  • Infectious Diseases

Background:

  • Coronavirus disease 2019 (COVID-19) has affected millions globally, with many survivors experiencing persistent symptoms.
  • Long-term neurological sequelae, such as debilitating headaches, are increasingly reported post-COVID-19 infection.
  • Refractory headaches pose a significant challenge in post-COVID-19 care.

Purpose of the Study:

  • To report the first successful treatment of a persistent COVID-19-related headache.
  • To evaluate the efficacy of a transnasal sphenopalatine ganglion block for post-viral headache.

Main Methods:

  • A case study of a female patient in her early 50s with a 5-month history of daily, severe, retro-orbital headaches following COVID-19.
  • The headache was resistant to standard analgesic medications.
  • Treatment involved a single transnasal sphenopalatine ganglion block.

Main Results:

  • The patient experienced complete resolution of her debilitating headache after the procedure.
  • The transnasal sphenopalatine ganglion block provided immediate and sustained relief.
  • This intervention effectively managed a persistent post-COVID-19 neurological symptom.

Conclusions:

  • Transnasal sphenopalatine ganglion block is a potential therapeutic option for persistent headaches after COVID-19.
  • This minimally invasive procedure offers a novel approach to managing long-term post-viral neurological complications.
  • Further research is warranted to explore the broader application of this technique in post-infectious headache management.