Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

9.1K
Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
9.1K
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

2.5K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.5K
Reconstruction of Signal using Interpolation01:10

Reconstruction of Signal using Interpolation

320
Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next...
320
Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

6.1K
Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
6.1K
Two-Dimensional Microscopy in Microbiology01:29

Two-Dimensional Microscopy in Microbiology

461
Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...
461

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complementary hyperpolarized <sup>13</sup>C and <sup>15</sup>N MRI reveal divergent signatures of hepatic injury and methyl-donor metabolism.

Npj imaging·2026
Same author

Intensity difference squeezing in a strongly overcoupled silicon nitride microresonator.

Optics letters·2026
Same author

Continuously tunable super-efficient microcombs.

Optics express·2026
Same author

Across-cities transportable <sup>13</sup>C hyperpolarization using UV-induced labile radicals.

Nature communications·2026
Same author

NRF2 controls a diverse network of antiviral effectors with p62 acting as a central restriction factor effective across virus families.

Redox biology·2026
Same author

Contrast-Enhanced VM-UNet for Thyroid Nodule Segmentation Based on Wavelet Features and Dual-Branch Edge Learning.

Journal of imaging informatics in medicine·2026

Related Experiment Video

Updated: Sep 6, 2025

Compact Lens-less Digital Holographic Microscope for MEMS Inspection and Characterization
10:28

Compact Lens-less Digital Holographic Microscope for MEMS Inspection and Characterization

Published on: July 5, 2016

10.4K

Differential phase reconstruction of microcombs.

Krishna Twayana, Fuchuan Lei, Zhichao Ye

    Optics Letters
    |July 1, 2022
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a new technique for measuring the spectral phase of microcombs. The method achieves high sensitivity and broad bandwidth, overcoming previous experimental challenges.

    More Related Videos

    Lens-free Video Microscopy for the Dynamic and Quantitative Analysis of Adherent Cell Culture
    09:04

    Lens-free Video Microscopy for the Dynamic and Quantitative Analysis of Adherent Cell Culture

    Published on: February 23, 2018

    9.6K
    Quantitative Optical Microscopy: Measurement of Cellular Biophysical Features with a Standard Optical Microscope
    14:09

    Quantitative Optical Microscopy: Measurement of Cellular Biophysical Features with a Standard Optical Microscope

    Published on: April 7, 2014

    15.7K

    Related Experiment Videos

    Last Updated: Sep 6, 2025

    Compact Lens-less Digital Holographic Microscope for MEMS Inspection and Characterization
    10:28

    Compact Lens-less Digital Holographic Microscope for MEMS Inspection and Characterization

    Published on: July 5, 2016

    10.4K
    Lens-free Video Microscopy for the Dynamic and Quantitative Analysis of Adherent Cell Culture
    09:04

    Lens-free Video Microscopy for the Dynamic and Quantitative Analysis of Adherent Cell Culture

    Published on: February 23, 2018

    9.6K
    Quantitative Optical Microscopy: Measurement of Cellular Biophysical Features with a Standard Optical Microscope
    14:09

    Quantitative Optical Microscopy: Measurement of Cellular Biophysical Features with a Standard Optical Microscope

    Published on: April 7, 2014

    15.7K

    Area of Science:

    • Nonlinear optics
    • Quantum optics
    • Spectroscopy

    Background:

    • Measuring microcomb amplitude and phase offers critical insights into nonlinear cavity dynamics.
    • Spectral phase measurements in microcombs are experimentally demanding.

    Purpose of the Study:

    • To develop a sensitive and broadband technique for differential spectral phase measurement of microcombs.
    • To overcome the experimental challenges associated with traditional spectral phase measurement methods.

    Main Methods:

    • A linear heterodyne technique was employed, aided by electro-optic downconversion.
    • The technique enables differential phase measurement across a wide spectral range.

    Main Results:

    • The method demonstrates unprecedented sensitivity of -50 dBm.
    • Broad bandwidth coverage exceeding 110 nm in the telecommunications range was achieved.
    • The technique was successfully validated on single-cavity and photonic molecule microcombs.

    Conclusions:

    • The developed technique significantly advances the ability to measure microcomb spectral phase.
    • This advancement opens new avenues for studying nonlinear cavity dynamics and microcomb applications.