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Multiple suicide attempts associated with addiction to tramadol
Bénédicte Nobile1,2,3, Marine Bonnin4, Emilie Olié4,5,6
1Department of Emergency Psychiatry and Acute Care, Lapeyronie Hospital CHU Montpellier, Montpellier, France. benedicte.nobile@gmail.com.
Annals of General Psychiatry
|July 1, 2022
Summary
This case study highlights a young woman
Area of Science:
- Neuroscience
- Psychiatry
- Pharmacology
Background:
- Tramadol, an opioid analgesic, is increasingly considered for major depressive disorder.
- Evidence links opioid system dysfunction to suicidal behaviors.
- Concerns exist regarding tramadol's addictive and suicidal risk.
Purpose of the Study:
- To present a case of tramadol addiction leading to suicide attempts.
- To question tramadol's prescription for individuals at risk of suicide.
Main Methods:
- Case report of a 25-year-old woman admitted for suicide attempt.
- Suicide attempt followed abrupt tramadol withdrawal after daily intake of 2000 mg.
- Patient history of tramadol addiction for pain management and psychological relief.
Main Results:
- Tramadol withdrawal exacerbated psychological pain and suicidal ideation.
- The patient experienced multiple suicide attempts linked to tramadol addiction.
- High daily tramadol dosage (2000 mg) was required for desired effects.
Conclusions:
- Tramadol addiction can precipitate severe psychological distress and suicidal behavior.
- This case underscores the potential risks of tramadol, challenging its perceived lower abuse potential.
- Caution is advised when prescribing tramadol, especially to individuals with a history of suicidal ideation or addiction.
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