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An open chat with…Alexander Wlodawer.

Ioannis Tsagakis1, Alexander Wlodawer2

  • 1FEBS Open Bio Editorial Office, Cambridge, UK.

FEBS Open Bio
|July 2, 2022
PubMed
Summary
This summary is machine-generated.

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Structural biologist Alexander Wlodawer discusses his work on IL-4 and retroviral proteases. He shares insights on scientific competition, open data, and the impact of AlphaFold.

Area of Science:

  • Structural Biology
  • Biochemistry
  • Bioinformatics

Background:

  • Alexander Wlodawer, Senior Investigator at the National Cancer Institute's Center for Structural Biology, has a distinguished career since 1974.
  • He has held positions at prestigious institutions including Stanford University, the University of Cambridge, and the National Bureau of Standards.

Discussion:

  • Wlodawer shares experiences in determining the structures of Interleukin-4 (IL-4) and retroviral proteases.
  • He offers advice on navigating the challenges of scientific competition and the phenomenon of being "scooped" in research.

Key Insights:

  • The interview highlights Wlodawer's perspectives on the importance of open data sharing in scientific advancement.
  • He discusses the transformative potential of artificial intelligence tools like AlphaFold in structural biology.

Related Experiment Videos

Outlook:

  • Wlodawer's reflections provide valuable guidance for early-career scientists.
  • The discussion emphasizes the evolving landscape of structural biology research and data dissemination.