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Antibiotic-Resistant Infections Among Inpatients with Coronavirus Disease 2019 (COVID-19) in US Hospitals
James Baggs1, Ashley N Rose1, Natalie L McCarthy1
1Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Abstract:
We described bacterial/fungal coinfections and antibiotic-resistant infections among inpatients with a diagnosis of coronavirus disease 2019 (COVID-19) and compared findings in those with a diagnosis of influenza like illness. Less than 10% of inpatients with COVID-19 had bacterial/fungal coinfection. Longer lengths of stay, critical care stay, and mechanical ventilation contribute to increased incidence of hospital-onset infections among inpatients with COVID-19.
Insights
Bacterial and fungal coinfections were uncommon in hospitalized coronavirus disease 2019 (COVID-19) patients. However, longer hospital stays and critical care increased the risk of hospital-acquired infections in these patients.
Area of Science:
- Infectious Diseases
- Critical Care Medicine
- Pulmonology
Background:
- Hospitalized patients with coronavirus disease 2019 (COVID-19) face risks of secondary infections.
- Understanding coinfection patterns and risk factors for hospital-onset infections is crucial for patient management.
Purpose of the Study:
- To describe bacterial/fungal coinfections and antibiotic-resistant infections in COVID-19 inpatients.
- To compare these findings with patients diagnosed with influenza-like illness (ILI).
- To identify factors contributing to hospital-onset infections in COVID-19 patients.
Main Methods:
- Retrospective analysis of inpatient data.
- Comparison of infection rates between COVID-19 and ILI cohorts.
- Identification of risk factors for hospital-acquired infections.
Main Results:
- Bacterial/fungal coinfections were present in less than 10% of COVID-19 inpatients.
- Longer lengths of stay, critical care admission, and mechanical ventilation were associated with higher incidence of hospital-onset infections.
- Incidence of coinfections in COVID-19 patients was compared to ILI patients (specific data not detailed in abstract).
Conclusions:
- Bacterial/fungal coinfections are not highly prevalent in COVID-19 inpatients.
- Hospital-acquired infections are a significant concern for COVID-19 patients requiring prolonged or intensive care.
- Proactive monitoring and infection control measures are essential for critically ill COVID-19 patients.
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