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Updated: Sep 6, 2025

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities
Published on: February 20, 2021
Dosimetry audit for megavoltage photon beams applied in non-reference conditions
Muhammad Safwan Ahmad Fadzil1, Noramaliza Mohd Noor2, Ung Ngie Min3
1Department of Radiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia; Diagnostic Imaging and Radiotherapy Program, Centre for Diagnostic, Therapeutic and Investigative Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300 Kuala Lumpur, Malaysia.
This Malaysian study shows that postal dosimetry audits effectively identify and resolve radiotherapy dose errors. Thermoluminescent dosimeters (TLDs) are crucial for ensuring accurate external beam radiation therapy.
Area of Science:
- Medical Physics
- Radiotherapy Dosimetry
- Quality Assurance in Radiation Oncology
Background:
- Accurate dose delivery is critical in external beam radiotherapy.
- Non-reference conditions pose challenges for dosimetry accuracy.
- Systematic errors in the dosimetry chain can compromise patient safety.
Purpose of the Study:
- To conduct the first Malaysian postal dosimetry audit for external beam radiotherapy under non-reference conditions.
- To evaluate output performance and screen for systematic errors in the dosimetry chain.
- To investigate detector choices and identify sources of discrepancies.
Main Methods:
- Audited ten radiotherapy centers, covering 16 megavoltage photon beam arrangements.
- Utilized the IAEA postal dosimetry protocol for non-reference conditions.
- Employed three types of thermoluminescent dosimeters (TLDs): Ge-doped cylindrical silica fibres (CF), Ge-doped flat silica fibres (FF), and TLD-100 powder.
Main Results:
- Eight centers met the ±5% dose tolerance; one exceeded it, and one failed initial irradiations.
- Post-remedial measures, mean relative responses for CF, FF, and TLD-100 were 1.00, 0.99, and 0.98.
- Coefficients of variation for CF, FF, and TLD-100 were 6.87%, 6.45%, and 5.06% respectively.
Conclusions:
- High-quality postal dosimetry audits using sensitive TLDs are effective in identifying dose discrepancies.
- These audits aid in resolving dose delivery issues in clinical radiotherapy practice.
- The study highlights the importance of regular audits for maintaining radiotherapy quality.
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