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Aortic Valve Repair in Pediatric Patients: 30 Years Single Center Experience
Johanna Schlein1, Alexandra Kaider2, Harald Gabriel3
1Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Insights
Pediatric aortic valve repair offers a successful long-term solution for congenital heart disease, with good survival rates and a repair-first strategy proving effective. Longevity outcomes were similar for both simple and complex aortic valve reconstruction techniques.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Congenital Heart Disease
Background:
- Valve repair is the preferred treatment for congenital aortic valve disease.
- Surgical techniques for aortic valve repair have advanced over time.
- This study reviews 30 years of pediatric aortic valve repair experience.
Purpose of the Study:
- To evaluate the long-term outcomes of pediatric aortic valve repair.
- To assess survival rates and the need for reoperations.
- To support a repair-first strategy for congenital aortic valve disease.
Main Methods:
- Retrospective review of 126 pediatric patients (<18 years) undergoing aortic valve repair (May 1985-April 2020).
- Mortality data cross-checked with national health insurance database.
- Primary endpoints: survival and reoperation incidence.
Main Results:
- Early mortality was 5.6%, primarily in neonates with critical aortic stenosis.
- No early deaths observed after 2002.
- 30-year estimated survival: 83.5%. Cumulative incidence of aortic valve replacement at 30 years: 67.4%. Nine patients required re-repair; most replacements were Ross procedures.
Conclusions:
- A repair-first strategy is supported for congenital heart disease.
- Aortic valve reconstruction can be a successful long-term solution.
- Longevity did not differ between simple commissurotomy and complex reconstruction.
Background:
Valve repair is the procedure of choice for congenital aortic valve disease. With increasing experience, the surgical armamentarium broadened from simple commissurotomy to more complex techniques. We report our 30-year experience with pediatric aortic valve repair.
Methods:
A retrospective chart review of all patients aged less than 18 years who underwent aortic valve repair from May 1985 to April 2020 was conducted. Mortality was cross-checked with the national health insurance database (96% complete mortality follow-up in April 2020). Primary study endpoints were survival and incidence of reoperations.
Results:
From May 1985 until April 2020, 126 patients underwent aortic valve repair at a median age of 1.8 years (interquartile range, 0.2-10). Early mortality was 5.6% (7 of 126). All early deaths occurred in neonates with critical aortic stenosis undergoing commissurotomy. No early deaths were observed after 2002. Kaplan-Meier estimated survival was 90.8% (95% CI, 84.0-94.8) at 10 years, 86.9% (95% CI, 78.7-92.2) at 20 years, and 83.5% (95% CI, 71.7-90.6) at 30 years. The cumulative incidence of aortic valve replacement was 37% (95% CI, 27.7-46.3) at 10 years, 62.2% (95% CI, 50.1-72.1) at 20 years, and 67.4% (51.2-79.2) at 30 years. Nine patients had undergone re-repair of the aortic valve. The majority of valve replacements were Ross procedures.
Conclusions:
Our results support a repair-first strategy for patients with congenital heart disease and underline that aortic valve reconstruction can be a successful long-term solution. Longevity did not differ between aortic valve commissurotomy and complex aortic valve reconstruction.
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