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Data-driven commentary on SARS-CoV-2 infection, vaccination, and fertility
Sigal Klipstein1, Jodie A Dionne2, Eve C Feinberg3
1Department of Obstetrics and Gynecology, Pritzker School of Medicine, University of Chicago, Chicago, Illinois; InVia Fertility Specialists, Hoffman Estates, Illinois.
Fertility and Sterility
|July 2, 2022
Summary
COVID-19 vaccination is safe for those trying to conceive or who are pregnant. A recent study found no impact of the vaccine on fecundity, supporting recommendations for preconceptual and early pregnancy vaccination.
Area of Science:
- Reproductive health
- Vaccinology
- Epidemiology
Background:
- Growing body of research indicates COVID-19 vaccination safety for pregnant individuals.
- Heightened risk of severe COVID-19 disease during pregnancy necessitates vaccination.
- American Society for Reproductive Medicine COVID-19 Task Force provides data-driven recommendations.
Purpose of the Study:
- To assess the effect of COVID-19 vaccination on fecundity in individuals attempting conception.
- To reinforce evidence-based recommendations for COVID-19 vaccination in preconceptual and pregnant populations.
Main Methods:
- Study population: Individuals with no known infertility attempting conception.
- Exposure: COVID-19 vaccination.
- Outcome: Effect on fecundity (ability to conceive).
Main Results:
- No statistically significant effect of COVID-19 vaccination on fecundity was observed.
- Findings support the safety of COVID-19 vaccines for individuals seeking pregnancy.
Conclusions:
- COVID-19 vaccination does not negatively impact the ability to conceive.
- Encourages vaccination during the preconceptual window and early pregnancy for optimal health outcomes.
- Supports continued research for safe reproductive-age healthcare during health crises.
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