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Refractive error characteristics and influence on ocular parameters in patients with unilateral congenital ptosis
Yingli Liu1, Tingting Chen1, Jingwen Huang1
1Department of Ophthalmology, First Affiliated Hospital of Sun Yat-sen University, 58 Zhongshan 2nd Road, Yuexiu District, Guangzhou, Guangdong Province, 510080, P. R. China.
Insights
Congenital ptosis affects ocular parameters, leading to thicker, flatter corneas and potentially lower visual acuity in affected eyes. This study compared these differences in unilateral cases.
Area of Science:
- Ophthalmology
- Ocular Biometry
- Refractive Error
Background:
- Unilateral congenital ptosis can impact visual development and ocular health.
- Understanding ocular parameter differences is crucial for managing ptosis patients.
Purpose of the Study:
- To investigate differences in refractive status and ocular parameters between ptotic and fellow eyes in unilateral congenital ptosis.
- To analyze the influence of congenital ptosis on corneal thickness, curvature, and visual acuity.
Main Methods:
- Thirty patients with unilateral congenital ptosis underwent comprehensive refractive and ocular biometric examinations.
- Measurements included axial length, central corneal thickness, anterior chamber depth, and keratometry using an IOL Master 700.
- Statistical analysis compared parameters between ptotic and fellow eyes.
Main Results:
- Ptotic eyes exhibited lower best-corrected visual acuity (BCVA) and a higher incidence of amblyopia.
- Central corneal thickness (CCT) was significantly greater in ptotic eyes.
- Corneas in ptotic eyes were flatter, with lower K1 and Km values, while axial length showed no significant difference.
Conclusions:
- Unilateral congenital ptosis is associated with significant changes in ocular parameters, notably a thicker and flatter cornea.
- Ptotic eyes may present with reduced BCVA and an increased risk of amblyopia.
- These findings highlight the importance of monitoring ocular health in patients with congenital ptosis.
Background:
The study aimed to investigate the difference in refractive status and ocular parameters between ptotic and fellow eyes in patients with unilateral congenital ptosis.
Methods:
Thirty patients (53% males, age 22.00 ± 11.41 years) with unilateral congenital ptosis diagnosed and treated at the First Affiliated Hospital of Sun-yat Sen University were enrolled and underwent detailed refractive examinations from March 2019 to February 2022. Ocular biometric measurements were performed by an IOL Master 700 biometer. The differences in refractive error characteristics, best-corrected visual acuity (BCVA), and ocular parameters including axial length (AL), central corneal thickness (CCT), aqueous depth (AQD), anterior chamber depth (ACD), lens thickness (LT), and keratometry values between ptotic and fellow eyes were analysed.
Results:
A lower BCVA (logMAR, median (IQR), 0.00 (- 0.13,0.00), P = 0.009) and a higher incidence of amblyopia (n (%), 7(23%), P = 0.016) were observed in ptotic eyes. The CCT of ptotic eyes was greater than that of fellow eyes (mean ± SD, 539.83 ± 26.73 μm, P < 0.001). The keratometry values at the flat axis (K1) and mean corneal power (Km) were smaller in ptotic eyes (mean ± SD, 42.11 ± 1.49 D, 42.68 ± 1.52 D, respectively, both P = 0.001). There was no significant difference in AL between ptotic and fellow eyes.
Conclusions:
Congenital ptosis influences ocular parameters, mainly causing a thicker and flatter cornea. Patients with unilateral congenital ptosis might have lower BCVA in the ptotic eyes.
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