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Updated: Sep 6, 2025
Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
Direct pulp capping in asymptomatic carious primary molars using three different pulp capping materials: a
K Chatzidimitriou1, G Vadiakas2, D Koletsi3
1Department of Pediatric Dentistry, School of Dentistry, National and Kapodistrian University of Athens, 2 Thivon Street, Goudi, 115 27, Athens, Greece. konchatzid@dent.uoa.gr.
Purpose:
Τo assess the outcome of direct pulp capping in asymptomatic carious primary molars using three pulp capping materials.
Methods:
In this prospective clinical trial, carious primary molars free of irreversible pulp inflammation signs and symptoms, with negative pain history and pulp exposure following caries removal were included. Teeth were divided into groups: A: Ca(OH)2, B: Pure Portland cement®, C: Biodentine™. Following anaesthesia, isolation, caries removal, pulp exposure, hemorrhage control, pulp capping, additional lining in groups A, B, teeth were restored with composite resin. Descriptive statistics, Chi-squared and Fisher's exact tests, Kaplan-Meier survival curves, multivariable random effects Cox regression model were performed.
Results:
Sixty-six patients (25 girls, 41 boys) with mean age 7.2 (± 1.7) years participated. The mean follow-up time was 13 months. Seventy-nine primary molars were assigned to groups A (n = 27), B (29), C (n = 23). The overall failure was 16% and the distribution by group was: A: 5 teeth, B: 5 teeth, C: 3 teeth. No significant differences in failure rates between capping materials, tooth types, age bands and genders were identified.
Conclusions:
Direct pulp capping in asymptomatic carious primary molars may be an acceptable option, when treating an exposed pulp with bioceramic materials as pulp capping agents.
