Related Experiment Video
Updated: Sep 6, 2025

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Gender-specific differences in hemodialysis patients: a multicenter longitudinal study from Serbia
Ljubica Djukanović1,2, Višnja Ležaić3,4, Nada Dimković3,4
1Academy of Medical Sciences of Serbian Medical Society, Belgrade, Serbia. ljubicadjukanovic@yahoo.com.
Gender differences exist in hemodialysis (HD) patients, impacting blood pressure and treatment, but not due to unequal care. These findings are crucial for understanding HD patient outcomes.
Area of Science:
- Nephrology
- Clinical Medicine
- Public Health
Background:
- Hemodialysis (HD) is a critical treatment for end-stage renal disease.
- Understanding gender-specific factors in HD patients is essential for optimizing care.
- Previous research has not fully elucidated longitudinal gender differences in HD populations.
Purpose of the Study:
- To investigate gender-specific differences in incident hemodialysis patients.
- To analyze how these differences evolve over time during hemodialysis treatment.
- To identify factors influencing outcomes in male and female HD patients.
Main Methods:
- Retrospective longitudinal closed cohort study.
- Involved 441 incident hemodialysis patients followed for 1-59 months.
- Data abstracted included demographics, clinical characteristics, treatment, labs, and outcomes.
Main Results:
- Males constituted about twice the number of females on HD.
- Females showed a greater decrease in systolic blood pressure over time.
- Females generally had higher spKt/V, while males had higher creatinine and CRP levels.
Conclusions:
- Significant gender differences were observed in hemodialysis patients.
- Some differences emerged during the study period.
- Observed differences were not attributable to gender-based treatment inequalities.
Related Concept Videos
Hemodialysis I: Introduction
Hemodialysis II: Procedure and Complications
Hemodialysis III: Nursing Management
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Serum Studies: Renal Function Tests
Acute Kidney Injury IV: Diagnostic Studies and Prevention

