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A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

Ambulatory heart rate and ST-segment depression during painful and silent myocardial ischemia in chronic stable

G P Carboni, A Lahiri, P M Cashman

    The American Journal of Cardiology
    |May 1, 1987
    PubMed

    Insights

    Heart rate and ST-segment depression during ischemia were studied in coronary artery disease patients. Ambulatory monitoring showed similar heart rates but greater ST-segment depression during ischemic episodes compared to exercise tests.

    Area of Science:

    • Cardiology
    • Clinical Exercise Physiology

    Background:

    • Obstructive coronary artery disease (CAD) can cause angina.
    • Ischemic ST-segment depression is a key indicator of myocardial ischemia.

    Purpose of the Study:

    • To investigate the relationship between heart rate and ST-segment depression during ischemic episodes in patients with CAD.
    • To compare ambulatory ischemic events with exercise-induced ischemia.

    Main Methods:

    • Seventy patients with documented CAD and angina underwent treadmill exercise testing.
    • 24-hour ambulatory electrocardiographic monitoring was conducted.
    • Data were compared between exercise tests and ambulatory monitoring.

    Main Results:

    • No significant difference in heart rate was observed between exercise and ambulatory monitoring during ischemic episodes.
    • Ambulatory monitoring revealed a greater magnitude of ST-segment depression during ischemic episodes compared to exercise-induced ischemia (p < 0.05).
    • A significant portion (64%) of ST-segment depression episodes were asymptomatic.

    Conclusions:

    • Heart rate during ischemic episodes is similar whether induced by exercise or occurring spontaneously.
    • ST-segment depression during spontaneous ischemia may be more pronounced than during exercise-induced ischemia.
    • Asymptomatic ST-segment depression is common in patients with CAD.

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